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dc.contributor.authorReis Costa, Pedro
dc.contributor.authorGiráldez Fernández, Jorge 
dc.contributor.authorRodrigues, Susana Margarida
dc.contributor.authorLeao Martins, José Manuel 
dc.contributor.authorPinto, Estefanía
dc.contributor.authorSoliño, Lucía
dc.contributor.authorGago Martínez, Ana María Consuelo
dc.date.accessioned2021-05-05T11:54:54Z
dc.date.available2021-05-05T11:54:54Z
dc.date.issued2021-03-31
dc.identifier.citationToxins, 13(4): 250 (2021)spa
dc.identifier.issn20726651
dc.identifier.urihttp://hdl.handle.net/11093/2094
dc.description.abstractTetrodotoxin (TTX) is a potent neurotoxin, considered an emerging toxin in Europe where recently a safety limit of 44 µg TTX kg−1 was recommended by authorities. In this study, three specimens of the large gastropod trumpet shell Charonia lampas bought in a market in south Portugal were analyzed using a neuroblastoma cell (N2a) based assay and by LC-MS/MS. N2a toxicity was observed in the viscera of two individuals analyzed and LC-MS/MS showed very high concentrations of TTX (42.1 mg kg−1) and 4,9-anhydroTTX (56.3 mg kg−1). A third compound with m/z 318 and structurally related with TTX was observed. In the edible portion, i.e., the muscle, toxin levels were below the EFSA recommended limit. This study shows that trumpet shell marine snails are seafood species that may reach the markets containing low TTX levels in the edible portion but containing very high levels of TTX in non-edible portion raising concerns regarding food safety if a proper evisceration is not carried out by consumers. These results highlight the need for better understanding TTX variability in this gastropod species, which is critical to developing a proper legal framework for resources management ensuring seafood safety, and the introduction of these gastropods in the markets.spa
dc.description.sponsorshipFundação para a Ciência e a Tecnologia | Ref. (UID/Multi/04326/2020)spa
dc.language.isoengspa
dc.publisherToxinsspa
dc.rightsAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleHigh levels of tetrodotoxin (TTX) in trumpet shell Charonia lampas from the Portuguese Coastspa
dc.typearticlespa
dc.rights.accessRightsopenAccessspa
dc.identifier.doi10.3390/toxins13040250
dc.identifier.editorhttps://www.mdpi.com/2072-6651/13/4/250spa
dc.publisher.departamentoQuímica analítica e alimentariaspa
dc.publisher.grupoinvestigacionInnovación en Agrolimentación y Salud: Aproximación multidisciplinar mediante análisis químico, neurofisiología, fisiología vegetal,microbiología y biotecnologíaspa
dc.subject.unesco3206.11 Toxicidad de Los Alimentosspa
dc.subject.unesco2301 Química Analíticaspa
dc.subject.unesco2302.90 Bioquímica de Alimentosspa
dc.date.updated2021-05-03T11:12:12Z


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    Attribution 4.0 International (CC BY 4.0)
    Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)