Multiregional tumor trees are not phylogenies

dc.contributor.author	Fernandes Alves, Joao Miguel
dc.contributor.author	Prieto Fernandez, Tamara
dc.contributor.author	Posada González, David
dc.date.accessioned	2022-04-21T07:21:27Z
dc.date.available	2022-04-21T07:21:27Z
dc.date.issued	2017-08
dc.identifier.citation	Trends in Cancer, 3(8): 546-550 (2017)	spa
dc.identifier.issn	24058033
dc.identifier.uri	http://hdl.handle.net/11093/3408
dc.description.abstract	Tumor samples most often comprise a mixture of different cell lineages. Multiregional trees built from bulk mutational profiles do not consider this heterogeneity and can potentially lead to erroneous evolutionary inferences, including biased timing of somatic mutations, spurious parallel mutation events, and/or incorrect chronological ordering of metastatic events.	en
dc.language.iso	eng	en
dc.publisher	Trends in Cancer	spa
dc.title	Multiregional tumor trees are not phylogenies	en
dc.type	article	spa
dc.rights.accessRights	openAccess	spa
dc.identifier.doi	10.1016/j.trecan.2017.06.004
dc.identifier.editor	https://linkinghub.elsevier.com/retrieve/pii/S2405803317301218	spa
dc.publisher.departamento	Bioquímica, xenética e inmunoloxía	spa
dc.publisher.grupoinvestigacion	Xenómica e Biomedicina	spa
dc.subject.unesco	2409 Genética	spa
dc.subject.unesco	2409.03 Genética de Poblaciones	spa
dc.date.updated	2022-04-21T07:17:26Z
dc.computerCitation	pub_title=Trends in Cancer\|volume=3\|journal_number=8\|start_pag=546\|end_pag=550	spa