RT Journal Article
T1 Potential health benefit of garlic based on human intervention studies: a brief Overview
A1 Ansary, Johura
A1 Forbes Hernández, Tamara Yuliett
A1 Gil Martin, Emilio
A1 Cianciosi, Danila
A1 Zhang, Jiaojiao
A1 Elexpuru Zabaleta, María
A1 Simal Gándara, Jesús
A1 Giampieri, Francesca
A1 Battino , Maurizio
K1 3309.20 Propiedades de Los Alimentos
K1 5101.13 Medicina Tradicional
K1 2302.90 Bioquímica de Alimentos
AB Garlic is a polyphenolic and organosulfur enriched nutraceutical spice consumed since ancient times. Garlic and its secondary metabolites have shown excellent health-promoting and disease-preventing effects on many human common diseases, such as cancer, cardiovascular and metabolic disorders, blood pressure, and diabetes, through its antioxidant, anti-inflammatory, and lipid-lowering properties, as demonstrated in several in vitro, in vivo, and clinical studies. The present review aims to provide a comprehensive overview on the consumption of garlic, garlic preparation, garlic extract, and garlic extract-derived bioactive constituents on oxidative stress, inflammation, cancer, cardiovascular and metabolic disorders, skin, bone, and other common diseases. Among the 83 human interventional trials considered, the consumption of garlic has been reported to modulate multiple biomarkers of different diseases; in addition, its combination with drugs or other food matrices has been shown to be safe and to prolong their therapeutic effects. The rapid metabolism and poor bioavailability that have limited the therapeutic use of garlic in the last years are also discussed.
PB Antioxidants
SN 20763921
YR 2020
FD 2020-07-15
LK http://hdl.handle.net/11093/1720
UL http://hdl.handle.net/11093/1720
LA eng
NO Antioxidants, 9(7): 619 (2020)
DS Investigo
RD 18-sep-2024