RT Journal Article
T1 The genus curcuma and inflammation: overview of the pharmacological perspectives
A1 Rahaman, Md. Moshiur
A1 Rakib, Ahmed
A1 Mitra, Saikat
A1 Tareq, Abu Montakim
A1 Emran, Talha Bin
A1 Shahid-Ud-Daula, A. F. M.
A1 Amin, Mohammad Nurul
A1 Simal Gándara, Jesús
K1 3209 Farmacología
K1 5101.13 Medicina Tradicional
K1 3309.20 Propiedades de Los Alimentos
AB The Curcuma genus has been extensively used for therapeutic purposes in traditional or folk medicine worldwide, including for its anti-inflammatory activity. Curcuma spp.’s active constituents, such as alkaloids, flavonoids, and terpenoids, can act on various targets in the signaling pathway, restrain pro-inflammatory enzymes, lower the production of inflammatory cytokines and chemokines, and reduce oxidative stress, which subsequently suppresses inflammatory processes. Preclinical and clinical studies have reported the predominant anti-inflammatory activity of several Curcuma species. This review provides an overview of the anti-inflammatory effects of different extracts, preparations, and bioactive components in this genus. This analysis may provide a scientific basis for developing new and alternative methods for the isolation of a single entity from this genus to attenuate inflammatory conditions. The Curcuma genus is waiting for researchers interested in developing safe and efficient anti-inflammatory agents for further investigation.
PB Plants
SN 22237747
YR 2020
FD 2020-12-30
LK http://hdl.handle.net/11093/1920
UL http://hdl.handle.net/11093/1920
LA eng
NO Plants, 10(1): 63 (2020)
DS Investigo
RD 16-sep-2024