RT Journal Article
T1 Molecular mechanisms of astaxanthin as a potential neurotherapeutic agent
A1 Bahbah, Eshak I.
A1 Ghozy, Sherief
A1 Attia, Mohamed S.
A1 Negida, Ahmed
A1 Emran, Talha Bin
A1 Mitra, Saikat
A1 Albadrani, Ghadeer M.
A1 Abdel Daim, Mohamed M.
A1 Uddin, Md. Sahab
A1 Simal Gándara, Jesús
K1 3207.11 Neuropatología
K1 3205.07 Neurología
K1 3209.90 Farmacología Experimental
AB Neurological disorders are diseases of the central and peripheral nervous system that affect millions of people, and the numbers are rising gradually. In the pathogenesis of neurodegenerative diseases, the roles of many signaling pathways were elucidated; however, the exact pathophysiology of neurological disorders and possible effective therapeutics have not yet been precisely identified. This necessitates developing multi-target treatments, which would simultaneously modulate neuroinflammation, apoptosis, and oxidative stress. The present review aims to explore the potential therapeutic use of astaxanthin (ASX) in neurological and neuroinflammatory diseases. ASX, a member of the xanthophyll group, was found to be a promising therapeutic anti-inflammatory agent for many neurological disorders, including cerebral ischemia, Parkinson’s disease, Alzheimer’s disease, autism, and neuropathic pain. An effective drug delivery system of ASX should be developed and further tested by appropriate clinical trials.
PB Marine Drugs
SN 16603397
YR 2021
FD 2021-04-03
LK http://hdl.handle.net/11093/2091
UL http://hdl.handle.net/11093/2091
LA eng
NO Marine Drugs, 19(4): 201 (2021)
NO Deanship of Scientific Research at Princess Nourah bint Abdulrahman University
DS Investigo
RD 26-sep-2023