RT Journal Article
T1 Stair climbing and mortality: a prospective cohort study from the UK Biobank
A1 Sanchez Lastra, Miguel Adriano
A1 Ding, Ding
A1 Dalene, Knut Eirik
A1 Pozo Cruz, Borja
A1 Ekelund, Ulf
A1 Tarp, Jakob
K1 2411.06 Fisiología del Ejercicio
K1 5204.04 Mortalidad
AB Background Regular stair climbing has the potential to lower the risk of premature death, but current evidence is scarce. Weaimed to examine whether daily stair climbing is associated with lower risk of all-cause, cancer, and cardiovascular disease(CVD) mortality.Methods Using the UK Biobank cohort, we extracted information of self-reported daily flights of stairs climbed at home,categorized as none, 1 to 5, 6 to 10, 11 to 15, and ≥16 flights per day. Associations between flights of stair climbed per dayand mortality were examined as hazard ratios (HRs) from Cox proportional hazards models adjusted for demographic, clinical,and behavioural covariates including time spent in other physical activities. We calculated the restricted mean survival time asan absolute measure of association. The risk of residual confounding was examined using propensity score matching and byusing lung cancer as negative control outcome. Participants were followed from baseline (2006–2010) through 31 March 2020.Results A total of 280 423 participants (median follow-up 11.1 years, during which 9445 deaths occurred) were included.Compared with not climbing any stairs, climbing more than five flights of stairs at home per day was associated with lowerrisk of premature mortality. The lowest risk was found for those climbing 6–10 flights per day: 0.91; 95% confidence interval(CI): 0.85, 0.98, translated to approximately 44 to 55 days of additional survival. A similar pattern was found after applyingpropensity score matching and for cancer mortality (6–10 flights per day HR: 0.88; 95% CI: 0.80, 0.97), but not for CVDmortality (6–10 flights per day HR: 1.08; 95% CI: 0.91, 1.29). The association between stair climbing and lung cancer was similar to that of all-cause mortality.Conclusions Climbing more than five flights of stairs at home per day was associated with a lower risk of all-cause and cancermortality, but not CVD mortality, compared with those who did not take the stairs. The magnitude of the association was smalland appeared susceptible to residual confounding. It is unlikely that at-home stair climbing is sufficient physical activity stimulito lower the risk of premature mortality
PB Journal of Cachexia Sarcopenia and Muscle
SN 21905991
YR 2021
FD 2021-02-04
LK http://hdl.handle.net/11093/3135
UL http://hdl.handle.net/11093/3135
LA eng
NO Journal of Cachexia Sarcopenia and Muscle, 12(2): 298-307 (2021)
DS Investigo
RD 13-sep-2024