RT Journal Article
T1 Silver nanoparticles produced by laser ablation and re-irradiation are effective preventing peri-implantitis multispecies biofilm formation
A1 Pérez Tanoira, Ramón
A1 Fernández Arias, Mónica
A1 Potel, Carmen
A1 Carballo Fernández, Raquel
A1 Pére -Castro, Sonia
A1 Boutinguiza Larosi, Mohamed
A1 Górgolas, Miguel
A1 Lusquiños Rodríguez, Fernando
A1 Pou Saracho, Juan María
K1 2209.10 láseres
K1 3311.03 Instrumentos Para Odontología
K1 2302 Bioquímica
AB Implant-associated infection due to biofilm formation is a growing problem. Given that silver nanoparticles (Ag-NPs) have shown antibacterial effects, our goal is to study their effect against multispecies biofilm involved in the development of peri-implantitis. To this purpose, Ag-NPs were synthesized by laser ablation in de-ionized water using two different lasers, leading to the production of colloidal suspensions. Subsequently, part of each suspension was subjected to irradiation one and three times with the same laser source with which it was obtained. Ag-NPs were immobilized on the surface of titanium discs and the resultant materials were compared with unmodified titanium coupons. Nanoparticles were physico-chemically analysed to determine their shape, crystallinity, chemical composition, and mean diameter. The materials were incubated for 90 min or 48 h, to evaluate bacterial adhesion or biofilm formation respectively with Staphylococcus aureus or oral mixed bacterial flora composed of Streptococcus oralis, Actinomyces naeslundii, Veionella dispar, and Porphyromonas gingivalis. Ag-NPs help prevent the formation of biofilms both by S. aureus and by mixed oral bacterial flora. Nanoparticles re-irradiated three times showed the biggest antimicrobial effects. Modifying dental implants in this way could prevent the development of peri-implantitis.
PB International Journal of Molecular Sciences
SN 14220067
YR 2022
FD 2022-10-10
LK http://hdl.handle.net/11093/3953
UL http://hdl.handle.net/11093/3953
LA eng
NO International Journal of Molecular Sciences, 23(19): 12027 (2022)
NO Xunta de Galicia | Ref. ED431C 2019/23
DS Investigo
RD 29-nov-2023