RT Journal Article T1 Colon cancer and colorectal cancer: Prevention and treatment by potential natural products A1 Islam, Md Rezaul A1 Akash, Shopnil A1 Rahman, Md Mominur A1 Nowrin, Feana Tasmim A1 Akter, Tamanna A1 Shohag, Sheikh A1 Rauf, Abdur A1 Aljohani, Abdullah S.M. A1 Simal Gándara, Jesús K1 3207.03 Carcinogénesis K1 3210 Medicina Preventiva K1 3209.07 Fitofármacos AB Colon cancer affects both men and women and is the world’s second most significant cause of cancer-relatedmortality. Colon cancer death rates have risen worldwide due to the current food habit and lifestyle, whichinclude a lot of meat, alcohol, and not enough physical exercise. As a result, novel, less harmful pharmacologicaltreatments for colon cancer are needed now more than ever before. Colorectal cancer (CRC) affects a significantportion of the world’s population. Chemotherapy’s limits, as demonstrated by side effects and resistance in CRCpatients, are now being sought after despite recent breakthroughs that have improved patient care and survival.Numerous chemical compounds present in medicinal herbs have shown anti-tumor and anti-apoptotic propertiesagainst various cancers, including CRC, in animal experiments. These chemicals, which come from severalphytochemical families, activate several signaling pathways. This article discusses research on the anti-CRCbenefits of many plants conducted in vitro, as well as the phytochemical components of plants that may play arole in the study. Researchers are also looking into the impact of these compounds on various pathways involvedin cancer signaling. According to this review, anti-CRC compounds may be generated from medicinal plants.That’s why we’re looking at how natural items can help treat cancer while lowering the risk of developing it. PB Chemico-Biological Interactions SN 00092797 YR 2022 FD 2022-12 LK http://hdl.handle.net/11093/4096 UL http://hdl.handle.net/11093/4096 LA eng NO Chemico-Biological Interactions, 368, 110170 (2022) NO Financiado para publicación en acceso aberto: Universidade de Vigo/CISUG DS Investigo RD 09-oct-2024