RT Journal Article T1 Biorefinery of brewery spent grain to obtain bioproducts with high value-added in the market A1 Outeiriño Rodríguez, David A1 Costa Trigo, Iván A1 Ochogavias, Aida A1 Pinheiro de Souza Oliveira, Ricardo A1 Pérez Guerra, Nelson A1 Salgado Seara, José Manuel A1 Domínguez González, José Manuel K1 3303 Ingeniería y Tecnología Químicas AB The brewery industry is under economic and environmental pressure to minimize residual management costs, particularly brewery spent grain (BSG), which accounts for 80–85% (w/w) of the total by-products generated. BSG is a lignocellulosic material primarily composed of carbohydrates, proteins and lipids. Developing a biorefinery model for conversion of BSG into value-added products is a plausible idea. Previous work optimized the pretreatment of BSG with the ionic liquid [N1112OH][Gly] and further release of fermentable sugar-containing solutions by enzymatic hydrolysis, using an enzymatic cocktail obtained by solid-state fermentation of BSGwith Aspergillus brasiliensis CECT 2700 and Trichoderma reesei CECT 2414. The current work ends the biorefinery process, studying the fermentation of these culture media with two LAB strains, Lactobacillus pentosus CECT 4023and Lactobacillus plantarum CECT 221, from which the production of organic acids, bacteriocins, and microbial biosurfactants (mBS) was obtained. In addition to the bacteriocin activity observed, a mass balance of the wholebiorefinery process quantified the production of 106.4 g lactic acid and 6.76 g mBS with L. plantarum and 116.1 g lactic acid and 4.65 g mBS with L. pentosus from 1 kg of dry BSG. Thus, BSG shows a great potential for waste valorization, playing a major role in the implementation of biomass biorefineries in circular bioeconomy. PB New Biotechnology SN 18716784 YR 2024 FD 2024-03 LK http://hdl.handle.net/11093/5648 UL http://hdl.handle.net/11093/5648 LA eng NO New Biotechnology, 79, 111-119 (2024) NO Agencia Estatal de Investigación | Ref. PID2020–115879RB-I00 DS Investigo RD 16-sep-2024